In April of this year (2022), a paper was published that demonstrated that patients who had received a lung transplant were experiencing lung transplant rejection due to what appeared to be antibody-mediated rejection.
Antibody-mediated rejection is an endothelial disorder, independent researcher Walter Chestnut wrote. “At long last, I see the bridge to the similarity of Graft vs Host disease and Covid/Long Covid/SPED (Spike Protein Endothelial Disease) … Clearly, it must be the Spike Protein.”
Why Covid/Long Covid/SPED Mimics Graft vs Host Disease by Walter M Chestnut
In April of this year (2022), a paper was published that demonstrated that patients who had received a lung transplant were experiencing lung transplant rejection (“LTR”) due to what appeared to be antibody-mediated rejection (“AMR”).
Limited antibody response to messenger RNA (mRNA) vaccines has been reported in LTR, with the majority mounting a response after the 2nd dose. In this series, 3 patients developed new and significant respiratory compromise after their 2nd vaccine dose consistent with antibody-mediated rejection (AMR).
Covid-19 Vaccine Triggered Rejection in Lung Transplant Recipients: A Case Series, The Journal of Heart and Lung Transplantation, April 2022
The operative words above are “consistent with.” However, what, actually, is antibody-mediated rejection? It is an endothelial disorder!
Antibody-mediated rejection (AMR) of solid organ transplants is characterised by the activation and injury of the allograft endothelium.
The Role of the Endothelium during Antibody-Mediated Rejection: From Victim to Accomplice, Frontiers, 29 January 2018
I believe the most critical factor to understand here, is that organ transplantation itself is very disruptive to the endothelium. The endothelium is already damaged, as it is in all risk factors for severe Covid.
At long last, I see the bridge to the similarity of Graft vs Host disease and Covid/Long Covid/SPED. Those who have been following my work will recall the observation I made long ago. Please search my Substack and research website for relevant posts.